Faculty Masood Ur Rehman Kayani

Masood Ur Rehman Kayani

Associate Professor
  • School of Interdisciplinary Engineering & Sciences
  • 0518865744
Summary

My current research focuses on the role of the human microbiome in health and disease and developing improved methods for microbiome data analysis. Specifically, my group is investigating the links between microbiome imbalances and conditions such as obesity, diabetes, and cancers, among others. Our goal is to uncover novel connections and identify biomarkers for early diagnosis, treatment response, and personalized medicine. Through our research, we hope to contribute to a deeper understanding of the complex interactions between the microbiome and human health, with the ultimate aim of improving disease diagnosis and treatment.

Academic Background
PhD (Bioinformatics) Tsinghua University September 17, 2012 - October 10, 2018
Honours and Awards
Publications
Genome-resolved metagenomics from short-read sequencing data in the era of artificial intelligence June 10, 2025 Functional and Integrative Genomics - Volume:25, Issue:1, Article Number 124
Efficient De Novo Assembly and Recovery of Microbial Genomes from Complex Metagenomes Using a Reduced Set of k-mers June 02, 2025 Interdisciplinary Sciences: Computational Life Sciences - Pages 1-14
Insights into the gut microbiome-metabolite dynamics in breast cancer April 09, 2025 Gut Microbes Reports - Pages 1-23
Prioritizing gut microbial SNPs linked to immunotherapy outcomes in NSCLC patients by integrative bioinformatics analysis March 17, 2025 Journal of Translational Medicine - Volume:23, Issue:1, Article Number: 343
Exploring the impact of type 2 diabetes and glucose‑lowering drugs on gut microbiome dynamics February 17, 2025 Discover Medicine - Volume 2, Article Number 47
Evaluating the potential of assembler-binner combinations in recovering low-abundance and strain-resolved genomes from human metagenomes January 30, 2025 Heliyon - Volume: 11, Issue: 2, Article Number: e41938, Pages: 15
MiCK: a database of gut microbial genes linked with chemoresistance in cancer patients December 21, 2024 Database: The Journal of Biological Databases and Curation - Vol. 2024: article ID baae124
Longitudinal analysis of exposure to a low concentration of oxytetracycline on the zebrafish gut microbiome September 22, 2022 Frontiers in Microbiology - Volume 13, Article Number 985065
Genome-Resolved Characterization of Structure and Potential Functions of the Zebrafish Stool Microbiome June 15, 2022 Frontiers in Cellular and Infection Microbiology - Volume 12, Article Number 910766
Patients with Primary and Secondary Bile Duct Stones Harbor Distinct Biliary Microbial Composition and Metabolic Potential April 25, 2022 Frontiers in Cellular and Infection Microbiology - Volume 12, Article Number 881489
Soil pH: a key edaphic factor regulating distribution and functions of bacterial community along vertical soil profiles in red soil of pomelo orchard February 01, 2022 BMC Microbiology - Volume 22, Issue 1, Article Number 38
Characterization of the Gastrointestinal and Reproductive Tract Microbiota in Fertile and Infertile Pakistani Couples December 28, 2021 Biology - Volume:11, Issue:1,
Genome-resolved metagenomics using environmental and clinical samples September 01, 2021 Briefings in Bioinformatics - Volume 22, Issue 5, Pages 1-20
Environmental concentrations of antibiotics alter the zebrafish gut microbiome structure and potential functions June 01, 2021 Environmental Pollution - Volume 278, Article Number 116760
Prediction and analysis of metagenomic operons via MetaRon: a pipeline for prediction of Metagenome and whole-genome opeRons January 19, 2021 BMC Genomics - Volume 22, Issue 1, Article Number: 60
DNA phosphorothioate modification facilitates the dissemination of mcr-1 and blaNDM-1 in drinking water supply systems January 01, 2021 Environmental Pollution - Volume 268, Part A, Article Number 115799
Dynamics of the Salivary Microbiome During Different Phases of Crohn's Disease October 06, 2020 Frontiers in Cellular and Infection Microbiology - Volume 10, Article Number 544704
Genome Sequences and Comparative Analysis of Two Extended-Spectrum Extensively-Drug Resistant Mycobacterium tuberculosis Strains December 18, 2018 Frontiers in Pharmacology - Volume 9, Article Number 1492
Metagenomic analysis of basal ice from an Alaskan glacier July 05, 2018 Microbiome - Volume 6, Issue 1, Article Number 123
Comprehensive analysis of circRNA expression bprofiles in humans by RAISE December 01, 2017 International Journal of Oncology - Volume 51, Issue 6, Pages 1625-1638
The essential mycobacterial amidotransferase GatCAB is a modulator of specific translational fidelity August 26, 2016 Nature Microbiology - Volume:1, Article Number 16147
Transmitted extended-spectrum extensively drug-resistant tuberculosis in Beijing, China, with discordant whole-genome sequencing analysis results August 01, 2015 Journal of Clinical Microbiology - Volume 53, Issue 8, Pages 2781-2784
Rapid identification of multi-strain HBV infection in patient by high-throughput DNA sequencing June 16, 2015 Quantitative Biology - Volume 3, Issue 2, Pages 103-106
Role of miRNAs in Breast Cancer December 01, 2011 Asian Pacific Journal of Cancer Prevention - Volume 12, Issue 12, Pages 3175-3180
Lack of Germ Line Changes in KISS1 and KAI1 Genes in Sporadic Head and Neck Cancer Patients of Pakistani Origin October 01, 2011 Asian Pacific Journal of Cancer Prevention - Volume 12, Issue 10, Pages 2767-2772
Conferences
Assistant Professor Capital University Of Science and Technology (CUST) November 15, 2022 - January 31, 2023
Belt and Road Young Scientist Xinhua Hospital, Shanghai China December 01, 2019 - September 30, 2022
International Exchange Postdoctoral Researcher Shanghai Institute of Immunology, School of Medicine, Shanghai Jiao Tong University February 01, 2019 - May 29, 2021